Expresión de búsqueda: SMALL LEUCINE-RICH PROTEOGLYCANS 
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Descriptor Inglés:   Small Leucine-Rich Proteoglycans 
Descriptor Español:   proteoglicanos pequeños ricos en leucina 
Descriptor Portugués:   Proteoglicanos Pequenos Ricos em Leucina 
Sinónimos Inglés:   SLRP Proteoglycans
Small Leucine Rich Proteoglycans
Small Leucine Rich Repeat Proteoglycan
Small Leucine Rich Repeat Proteoglycans
Small Leucine-Rich Repeat Proteoglycan
Small Leucine-Rich Repeat Proteoglycans  
Categoría:   D09.698.735.700
D12.776.395.650.875
D12.776.860.300.806
Definición Inglés:   A proteoglycan family (SLRPs) that is defined by a central domain which consists of a variable number of repeats of the motif LXXLxLXXNxL, where L may be LEUCINE; ISOLEUCINE; VALINE; or other hydrophobic amino acids. The N-terminal contains four conserved CYSTEINE residues and may be modified depending on function. SLRPs provide structural support to the EXTRACELLULAR MATRIX and are critical for regulating its assembly and dynamics at CELL-MATRIX JUNCTIONS. 
Nota Histórica Inglés:   2017 
Calificadores Permitidos Inglés:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Número del Registro:   56522 
Identificador Único:   D000071232 

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